From Escape swim network interneurons have diverse roles in behavioral switching and putative arousal in Pleurobranchaea.
Journal of neurophysiology.
Journal of neurophysiology.
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Fig. 1. Line drawing of the dorsal surface of the cerebropleural and pedal ganglia indicating locations of identified neuronal somata of networks for feeding (inset: MCG, PCP, PSE, PCT, 2 I1s, and 3 I2s), escape swimming (inset: A1, As1-4, A10, A3, and A-ci1), and locomotion (G neuron cluster). Filled circles: serotonin immunoreactive somata. Whereas bilaterally symmetrical, somata are only shown unilaterally for convenience. Cell abbreviations: MCG, metacerebral giant neuron; PCP, phasic paracerebral interneuron; PSE, polysynaptic excitor of the PCP; PCT, tonic paracerebral interneuron; I1, Interneuron 1; and I2, Interneuron 2. Nerve abbreviations, cerebropleural ganglion: BWN, body wall nerve; sBWN, small body wall nerve; CBC, cerebrobuccal connective; aCPC, anterior cerebropedal connective; pCPC, posterior cerebropedal connective; CVC, cerebrovisceral connective; MN, mouth nerve; OVN, oral veil nerve; RN, rhinophore nerve; SCC, subcerebral commissure; and TN, tentacle nerve. Pedal ganglion: aLBWN, anterior lateral body wall nerve; pLBWN, posterior lateral body wall nerve; PC, pedal commissure; pPC, parapedal commissure; aPN, anterior pedal nerve; mPN, medial pedal nerve; and pPN, posterior pedal nerve.
- Figure 1 shows the relative positions of the neuron cell bodies.
- Known premotor neurons that either compose the central pattern generator for escape swimming or receive outputs from it are found on the dorsal cerebral region of the cerebropleural ganglion, in a group called the A cluster (Fig. 1).
- Feeding behavior is inhibited during swim episodes in part by spike activity in the swim neuron A1, which was previously shown to activate a strong polysynaptic inhibitory pathway to the PCp feeding command neurons (Jing and Gillette 1995) (Fig. 1).